Natural variant R246K in hemagglutinin increased zoonotic characteristics and renal inflammation in mice infected with H9N2 influenza virusArticle Published on 2023-04-012023-06-22 Journal: Veterinary microbiology [Category] 조류인플루엔자, [키워드] Avian influenza virus H9N2 hemagglutinin pandemic Variation Zoonotic. [DOI] 10.1016/j.vetmic.2023.109667 PMC 바로가기
Research progress of biosensors for detection of SARS-CoV-2 variants based on ACE2Article Published on 2023-01-012022-11-15 Journal: Talanta [Category] SARS, 변종, 치료기술, [키워드] Accuracy ACE2 acute respiratory syndrome addition antibody biosensor biosensors caused Cell cells complex coronavirus coronavirus disease COVID-19 detect detection Diagnosis drug evaluated gold standard Health increase Interaction modulate Mutation Novel coronavirus pandemic Prevent receptor RT-PCR SARS-CoV-2 SARS-CoV-2 spike protein SARS-CoV-2 variant SARS-CoV-2 variants SARS-CoV-2. the spike protein time-consuming variants Variation virus virus mutations [DOI] 10.1016/j.talanta.2022.123813 PMC 바로가기
From Alpha to Omicron BA.2: New digital RT-PCR approach and challenges for SARS-CoV-2 VOC monitoring and normalization of variant dynamics in wastewaterArticle Published on 2022-11-202022-11-16 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, [키워드] approach circulation Concentration COVID-19 COVID-19 pandemic discrimination Epidemic fecal France Genome sequencing greater human population immune response immunized incidence Local MONITOR New normalization omicron Paris pathogenicity Patient PMMoV populations prevalent proportion public health resulting risk RT-PCR SARS-CoV-2 selection of variant Sequencing Severity of infection specific mutation Spread statistically strain subject suggested the SARS-CoV-2 genome Transmissibility Vaccination strategy Variability variant variants of concern Variation viral dynamics viral spread virus VoC VOCs wastewater Wastewater. [DOI] 10.1016/j.scitotenv.2022.157740 PMC 바로가기
Assessing a fossil fuels externality with a new neural networks and image optimisation algorithm: the case of atmospheric pollutants as confounders to COVID-19 lethalityOriginal Paper Published on 2022-11-162022-11-01 Journal: Epidemiology and Infection [Category] COVID-19, MERS, [키워드] adopted Affect Air pollution Algorithm approach Assessing atmospheric causal relationship China collected data confounder coronavirus COVID-19 COVID-19 epidemic deaths economic growth GDP generate Health image learning Implications machine learning network Neural neural networks Spread Transport turn Variation [DOI] 10.1017/S095026882100248X PMC 바로가기 [Article Type] Original Paper
Hotspot residues and resistance mutations in the nirmatrelvir-binding site of SARS-CoV-2 main protease: Design, identification, and correlation with globally circulating viral genomesArticle Published on 2022-11-122022-11-15 Journal: Biochemical and Biophysical Research Communication [Category] SARS, 변종, 치료제, [키워드] acute respiratory syndrome Adaptability Antiviral approved circulating coronavirus correlation COVID-19 cases COVID-19 pandemic develop drug resistance FDA highest hotspot intracellular protein Like M pro main protease Mild-to-moderate mutant Mutation mutations Nirmatrelvir offer omicron predicted Probability protease Protein design reported residue residues resistance resistance mutations robust SARS-CoV-2 SARS-CoV-2 lineage signature Signatures of adaptation. Surveillance unique variant Variation variations viral adaptation viral genome viruses [DOI] 10.1016/j.bbrc.2022.09.010 PMC 바로가기
Characterization and immunogenicity of SARS-CoV-2 spike proteins with varied glycosylationArticle Published on 2022-11-082022-11-15 Journal: Vaccine [Category] SARS, 진단, [키워드] 293 cells 293F cell acute respiratory syndrome addition binding caused Cell changed characterization convalescent sera coronavirus Coronavirus disease-19 COVID-19 Critical discrepancy effective Efficacy elicited exhibited expression globe glycosylated glycosylation glycosylation pattern homogeneity host cells IgG immunization immunogenicity insect cell mammalian cells mice Neutralizing antibody response neutralizing antibody titre pandemic Protein Proteins provide reactivity Receptor binding regimen robust S protein S-2P SARS-CoV-2 SARS-CoV-2 spike protein spike Spike. the S protein thermal stability Vaccine Vaccine design Variation virus virus entry while [DOI] 10.1016/j.vaccine.2022.09.057 PMC 바로가기
Identification of mutations in SARS-CoV-2 PCR primer regionsArticle Published on 2022-11-042022-11-15 Journal: Scientific Reports [Category] SARS, 변종, 치료기술, 치료제, [키워드] Accuracy Analysis anticipated approach dataset diagnostic Efficiency genomic variation gold standard identification Mutation Neutral omicron overlapping PCR PCR efficiency primer primer set primer sets Region RT-PCR Sample SARS-CoV-2 SARS-CoV-2 PCR SARS-CoV-2 viral strain susceptible target region the SARS-CoV-2 genome variant Variation [DOI] 10.1038/s41598-022-21953-3 PMC 바로가기
Chemical explosion, COVID-19, and environmental justice: Insights from low-cost air quality sensorsResearch article Published on 2022-11-012022-10-05 Journal: The Science of the total environment [Category] 유전자 메커니즘, [키워드] addition affecting Air quality monitoring Analysis anthropogenic association Chemical Community company comparable Concentration concentrations COVID-19 Critical disaster environmental justice EPA examined finding greater Houston identify indicate Industrial fire accident information insight ITC lockdown Low-cost sensor measure MONITOR monitors objective observation Particulate matter positive protection Regulatory Sociodemographic terminal Variation [DOI] 10.1016/j.scitotenv.2022.157881 [Article Type] Research article
Occurrence and distribution of azithromycin in wastewater treatment plants, seawater, and sediments of the northern part of the Persian Gulf around Bushehr port: A comparison with Pre-COVID 19 pandemicResearch article Published on 2022-11-012022-10-05 Journal: Chemosphere [Category] 변종, 치료기술, 치료제, [키워드] adjusted Antibiotic resistance Antibiotics assumed Azithromycin Bushehr collected Concentration Contamination COVID 19 COVID 19 patients disease distribution ecosystem Effect Efficiency evaluate growth Hypothesis indicated investigated less observation pandemic Persian gulf plant plants Seawater treat Treatment Variation variations Wastewater treatment plants [DOI] 10.1016/j.chemosphere.2022.135996 [Article Type] Research article
Angiotensin-converting enzyme 1 and voltage-gated potassium channel-interacting protein 4 gene polymorphisms in COVID-19 patients from east of IranArticle Published on 2022-11-012022-11-15 Journal: Clinica chimica acta; international journal of cli [Category] 진단, [키워드] ACE1 acute respiratory syndrome affecting Angiotensin-converting enzyme Angiotensin-converting enzyme 1 Care case-control study caused coronavirus Coronavirus disease 2019 COVID-19 COVID-19 pathogenesis COVID-19 patient COVID-19 susceptibility death disease enzyme Ethnic groups Factor Frequency Genetic Genotype genotyped Health healthy controls I/D polymorphism Infection Iran KCNIP4 material outcome pandemic pathogen PCR polymorphism Polymorphisms populations Potassium Prognostic factor Protein Region Research Respiratory disease severe acute respiratory syndrome coronavirus 2 severity statistically significant supported survival Variation Voltage-gated potassium (Kv) channel-interacting protein 4. [DOI] 10.1016/j.cca.2022.09.006 PMC 바로가기